At Palazzo di Varignana, a resort nestled in the hills of Bologna, a unique experience dedicated to longevity, health, well-being, and performance comes to life, inspired by the Acquaviva Method created by Dr. Annamaria Acquaviva – a pharmacist dietitian, expert in mindfulness and longevity science, and the resort’s Scientific Director.

Surrounded by a 700-hectare agricultural estate, vineyards, olive groves, lakes, one of Italy’s 100 most beautiful gardens, and a magnificent 4,000 sqm SPA, Palazzo di Varignana combines the charm of Italian tradition with a cutting-edge scientific approach.

The Acquaviva Method Retreats are integrated wellness programs based on the five pillars of health: functional nutrition, inner balance, physical activity, sleep and rest, and nutritional and cosmetic supplementation.

The programs are inspired by the principles of epigenetics, the discipline that studies how nutrition, physical activity, sleep, stress management, and lifestyle can influence personal well-being and contribute to a better quality of life over the long term.

Thanks to this holistic balance, the retreats promote reset and purification, deep detoxification, quality sleep, safe weight loss, hormonal balance, cellular regeneration, and renewed vitality.

The wellness programmes dedicated to weight loss include weight-loss stays and wellness weeks at the hotel, designed for those who wish to improve their lifestyle, support their metabolism and achieve their goals through a personalised journey with the support of professionals.

Each program can be tailored to individual needs, with the support of Dr. Acquaviva and her team.

Discover the retreats and begin your journey towards well-being and longevity.